Duration: 60 days
Criteria: Medically diagnosed patients, above the age of 3, with any form or stage of Alopecia Areata (patchy, totalis, universalis) are eligible to participate. Patients may or may not currently be under treatment by a doctor. Patients may or may not have comorbid disease expression.
Requirements: Participants must complete online daily logs, general information and alopecia areata survey, bi-weekly progress photos. Patients should continue on any MD-prescribed treatment while participating. Patients should discontinue any elective vitamin or dietary supplementation or OTC medications (not part of a medically prescribed therapy).
Cost to Participant: 325.00 (60-day session)
Description and Background: Intestinal microflora-gut dysbiosis pathogenesis in Alopecia Areata speculated.
(AA) is a frequently occurring, chronic, inflammatory disease which is expressed as varying degrees of unpredictable, non-scarring hair loss. Alopecia areata (AA) is hypothesized to be an organ-specific autoimmune disease mediated by T cells to the hair follicles. AA is marked by autoimmune assault on the hair follicle resulting in hair loss. There is a strong association with disease severity in alopecia areata and certain other autoimmune and inflammatory diseases. Despite some progress in the last decade, alopecia areata is still poorly understood.
The role of environmental factors, including emotional stress, in triggering disease onset or exacerbation remains speculative. The increased likelihood of comorbid autoimmune disease with AA negatively impacts the severity, prognosis, and treatment possibilities of AA. Currently there is no effective or reliable treatment for AA.
There is an increasing accumulation of evidence that bacterial pathogenesis occurring in the gut mediates certain autoimmune diseases. Additionally, research has shown that consumption of certain types of food can disrupt the relationship between the immune system and the beneficial mixed of bacteria in the intestine resulting in the release of strains that can set off “an unregulated tissue-damaging immune response which can be difficult to switch off”. Specifically regulated diet will alter the composition of the microbiome rapidly and has been shown to successfully regulate the gut environment. Diet can minimize inflammatory pathology within the body.
Does bacterial pathogenesis have a role in Alopecia Areata? Is dysbiosis of the microbiome an instigating and/or complicating mechanism in the pathogenesis of autoimmune alopecia areata?
RLT therapy is intended to restore intestinal homeostasis; support epithelial cell function; curb systemic inflammation; and promote superior metabolic/cellular health to reverse autoimmune Alopecia Areata expression and possibly comorbid conditions.
While the specific mechanism(s) of RLT Microbiotic therapy are not fully understood, recent findings in the rapidly-emerging field of human microbiome studies – which is identifying the critical relationship between human host and the microbial ecosystem of the intestinal tract (gut) and elucidating how disruptions to intestinal homeostasis (dysbiosis) can adversely impact immune function and lead to impaired health and disease – lend support to the RLT premise and its apparent effectiveness.
Further investigations are needed to confirm the role of microbiome dysbiosis and diminished epithelial cell function in the pathogenesis of AA. Further investigations are needed to confirm the exact role and efficacy of RLT therapy for treating Alopecia Areata, Totalis, Universalis.
- RLT Dietary Guide
- Prommune supplement 60-day supply
- Nutritional support/counseling throughout the RLT Monitored Session
RLT’s targeted nutrition approach employs the uniquely designed graduated oligoantigenic diet that has shown promise as a critical tool in reversing and maintaining continuing control over Alopecia Areata. This highly specialized diet is broken into 4 parts over 60 days.
The strictly controlled RLT diet is designed to lower the risk of sensitivity to food or additives that contribute to impaired health and immune function, while fortifying the body with foods that are known to have superior value in promoting health and curbing inflammation. Starting with a short ‘preparation’ stage, the diet then introduces an increasingly expanded menu of ‘medicinal’ foods in 1-week phases.
The specially formulated Prommune nutritional supplement is a formulation of 24 essential ingredients, in specific ratios designed to maximize absorption of vitamins and minerals to support microbiome and immune system function and counter inflammatory disease. The supplement formula is designed to be ingested daily. No other vitamins or minerals are recommended with the Prommune supplement formula. Prommune is provided in an easily absorbed powder form that can be blended into food or liquid.
Daily logs help us to measure and evaluate progress. This valuable response data is then used to improve our understanding of how effectively RLT therapy works. Unless we have properly documented logs and photos (anonymity maintained) we are unable to incorporate individual results within the larger data pool.
RLT therapy requires strict nutritional changes and can be challenging. Participants that receive support do best at maintaining the regimen. They can communicate directly when they have questions or concerns or simply need support. Routine communication also allows us to watch for physiological changes, make individual adjustments, and identify areas of concern that require closer scrutiny.